[HTML][HTML] Urinary cytokines reflect renal inflammation in acute tubulointerstitial nephritis: a multiplex bead-based assay assessment
L Martinez Valenzuela, J Draibe, O Bestard… - Journal of Clinical …, 2021 - mdpi.com
Background: Acute tubulointerstitial nephritis (ATIN) diagnosis lays on histological
assessment through a kidney biopsy, given the absence of accurate non-invasive
biomarkers. The aim of this study was to evaluate the accuracy of different urinary
inflammation-related cytokines for the diagnostic of ATIN and its distinction from acute
tubular necrosis (ATN). Methods: We included 33 patients (ATIN (n= 21), ATN (n= 12)), and
6 healthy controls (HC). We determined the urinary levels of 10 inflammation-related …
assessment through a kidney biopsy, given the absence of accurate non-invasive
biomarkers. The aim of this study was to evaluate the accuracy of different urinary
inflammation-related cytokines for the diagnostic of ATIN and its distinction from acute
tubular necrosis (ATN). Methods: We included 33 patients (ATIN (n= 21), ATN (n= 12)), and
6 healthy controls (HC). We determined the urinary levels of 10 inflammation-related …
MO335 URINARY CYTOKINES REFLECT THE ONGOING RENAL INFLAMMATION IN THE DIAGNOSTIC OF ACUTE TUBULOINTERSTITIAL NEPHRITIS: RESULTS …
L Martinez Valenzuela, J Draibe… - Nephrology Dialysis …, 2021 - academic.oup.com
Abstract Background and Aims Acute tubulointerstitial nephritis (ATIN) diagnostic lays on the
kidney biopsy given the absence of non-invasive biomarkers for disease demonstration and
follow-up. The aim of this study was to evaluate the accuracy of ten urinary inflammatory-
related cytokines in the diagnostic of ATIN and its clinical distinction from acute tubular
necrosis (ATN). Method Observational prospective study including 21 ATIN and 12 ATN
patients, and 6 healthy controls. We determined the urinary levels of 10 inflammation-related …
kidney biopsy given the absence of non-invasive biomarkers for disease demonstration and
follow-up. The aim of this study was to evaluate the accuracy of ten urinary inflammatory-
related cytokines in the diagnostic of ATIN and its clinical distinction from acute tubular
necrosis (ATN). Method Observational prospective study including 21 ATIN and 12 ATN
patients, and 6 healthy controls. We determined the urinary levels of 10 inflammation-related …