Individually distinct transplantation antigens of chemically induced mouse tumors

PK Srivastava, LJ Old - Immunology Today, 1988 - Elsevier
Tumor-specific antigens have been the philosopher's stone of tumor immunology. The best
candidates for these elusive molecules are the tumor rejection antigens of chemically
induced sarcomas of mice. Although much studied, these antigens have defied molecular
definition. As Pramod Srivastava and Lloyd Old review here, a recently discovered family of
96 kDa cell surface glycoproteins may hold the answer to this unresolved problem.