Expression profiles of cancer stem cell markers: CD133, CD44, Musashi-1 and EpCAM in the cardiac mucosa—Barrett's esophagus—early esophageal …
A Mokrowiecka, L Veits, C Falkeis, J Musial… - … -Research and Practice, 2017 - Elsevier
Introduction Barrett's esophagus (BE), which develops as a result of gastroesophageal reflux
disease, is a preneoplastic condition for esophageal adenocarcinoma (EAC). A new
hypothesis suggests that cancer is a disease of stem cells, however, their expression and
pathways in BE− EAC sequence are not fully elucidated yet. Aims We used a panel of
putative cancer stem cells markers to identify stem cells in consecutive steps of BE-related
cancer progression. Methods Immunohistochemistry was performed on formalin-fixed …
disease, is a preneoplastic condition for esophageal adenocarcinoma (EAC). A new
hypothesis suggests that cancer is a disease of stem cells, however, their expression and
pathways in BE− EAC sequence are not fully elucidated yet. Aims We used a panel of
putative cancer stem cells markers to identify stem cells in consecutive steps of BE-related
cancer progression. Methods Immunohistochemistry was performed on formalin-fixed …