Postprandial mineral metabolism and secondary hyperparathyroidism in early CKD
T Isakova, O Gutierrez, A Shah, L Castaldo… - Journal of the …, 2008 - journals.lww.com
Normophosphatemia and normocalcemia are maintained in chronic kidney disease (CKD)
by increased levels of fibroblast growth factor-23 (FGF-23) and parathyroid hormone (PTH),
but the stimuli for secretion of these hormones in early CKD are incompletely understood.
Most human physiologic studies have focused on random or fasting measurements of
phosphorus, calcium, FGF-23, and PTH, but in this study, the hypothesis was that
measurements in the postprandial state may reveal intermittent stimuli that lead to increased …
by increased levels of fibroblast growth factor-23 (FGF-23) and parathyroid hormone (PTH),
but the stimuli for secretion of these hormones in early CKD are incompletely understood.
Most human physiologic studies have focused on random or fasting measurements of
phosphorus, calcium, FGF-23, and PTH, but in this study, the hypothesis was that
measurements in the postprandial state may reveal intermittent stimuli that lead to increased …
