Circulating mitochondrial DNA as predictor of mortality in critically ill patients: a systematic review of clinical studies
JS Harrington, JW Huh, EJ Schenck, K Nakahira… - Chest, 2019 - Elsevier
Background Despite numerous publications on mitochondrial DNA (mtDNA) in the last
decade it remains to be seen whether mtDNA can be used clinically. We conducted a
systematic review to assess circulating cell-free mtDNA as a biomarker of mortality in
critically ill patients. Methods This systematic review was registered with PROSPERO
(CRD42016046670). PubMed, CINAHL, the Cochrane Library, Embase, Scopus, and Web
of Science, and reference lists of retrieved articles were searched. Studies measuring …
decade it remains to be seen whether mtDNA can be used clinically. We conducted a
systematic review to assess circulating cell-free mtDNA as a biomarker of mortality in
critically ill patients. Methods This systematic review was registered with PROSPERO
(CRD42016046670). PubMed, CINAHL, the Cochrane Library, Embase, Scopus, and Web
of Science, and reference lists of retrieved articles were searched. Studies measuring …