Effect of youth-onset type 2 diabetes mellitus on incidence of end-stage renal disease and mortality in young and middle-aged Pima Indians

ME Pavkov, PH Bennett, WC Knowler, J Krakoff… - Jama, 2006 - jamanetwork.com
ContextThe long-term outcome of persons with youth-onset type 2 diabetes mellitus has not
been well described. ObjectiveTo compare incidence of diabetic end-stage renal disease
(ESRD) and mortality in Pima Indians with youth-and older-onset type 2 diabetes mellitus.
Design, Setting, and ParticipantsLongitudinal population-based study conducted between
1965 and 2002 in Pima Indians from the state of Arizona. Participants were divided into 2
groups:(1) youth-onset type 2 diabetes mellitus (onset< 20 years of age) and (2) older-onset …