Embryo developmental arrest: Review of genetic factors and pathways
M Mohebi, S Ghafouri-Fard - Gene Reports, 2019 - Elsevier
Embryo developmental arrest (EDA) is a cause of infertility. As the assessment of the EDA-
associated phenotypes in situations rather than in vitro fertilization (IVF) is difficult, EDA is
described as cause of IVF failure. Chromosomal abnormalities, abnormal preimplantation
development and single gene disorders have been stated as causes of EDA. This process is
also associated with abnormal regulation of some signaling pathways such as Wnt and TGF-
β pathways. With the advent of high throughput sequencing techniques, the role of some …
associated phenotypes in situations rather than in vitro fertilization (IVF) is difficult, EDA is
described as cause of IVF failure. Chromosomal abnormalities, abnormal preimplantation
development and single gene disorders have been stated as causes of EDA. This process is
also associated with abnormal regulation of some signaling pathways such as Wnt and TGF-
β pathways. With the advent of high throughput sequencing techniques, the role of some …