[HTML][HTML] Clinical application of comprehensive chromosomal screening at the blastocyst stage

WB Schoolcraft, E Fragouli, J Stevens, S Munne… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To evaluate a new strategy for comprehensive chromosome screening at the
blastocyst stage. DESIGN: Clinical research study. SETTING: An IVF clinic and a specialist
preimplantation genetic diagnosis laboratory. PATIENT (S): Forty-five infertile couples
participated in the study. The mean maternal age was 37.7 years, and most couples had at
least one previous unsuccessful IVF treatment cycle (mean 2.4). INTERVENTION (S): This
study used a novel chromosome screening approach, combining biopsy of several …