Measuring influenza neutralizing antibody responses to A (H3N2) viruses in human sera by microneutralization assays using MDCK-SIAT1 cells
FL Gross, Y Bai, S Jefferson, C Holiday… - JoVE (Journal of …, 2017 - jove.com
Neutralizing antibodies against hemagglutinin (HA) of influenza viruses are considered the
main immune mechanism that correlates with protection for influenza infections.
Microneutralization (MN) assays are often used to measure neutralizing antibody responses
in human sera after influenza vaccination or infection. Madine Darby Canine Kidney (MDCK)
cells are the commonly used cell substrate for MN assays. However, currently circulating 3C.
2a and 3C. 3a A (H3N2) influenza viruses have acquired altered receptor binding specificity …
main immune mechanism that correlates with protection for influenza infections.
Microneutralization (MN) assays are often used to measure neutralizing antibody responses
in human sera after influenza vaccination or infection. Madine Darby Canine Kidney (MDCK)
cells are the commonly used cell substrate for MN assays. However, currently circulating 3C.
2a and 3C. 3a A (H3N2) influenza viruses have acquired altered receptor binding specificity …