Malaria: Successful Immunization Against the Sexual Stages of Plasmodium gallinaceum

RW Gwadz - Science, 1976 - science.org
RW Gwadz
Science, 1976science.org
Gametocyte infectivity and oocyst development of the avian malaria parasite, Plasmodium
gallinaceum, can be reduced or eliminated in mosquitoes by immunizing the chickens on
which the mosquitoes feed with infected red blood cells that have been treated with formalin
or x-rays. Protection of the mosquito appears to be related to the immobilization of the
microgametes in its gut and is associated with the immunoglobulin G fraction of serum.
Gametocyte infectivity and oocyst development of the avian malaria parasite, Plasmodium gallinaceum, can be reduced or eliminated in mosquitoes by immunizing the chickens on which the mosquitoes feed with infected red blood cells that have been treated with formalin or x-rays. Protection of the mosquito appears to be related to the immobilization of the microgametes in its gut and is associated with the immunoglobulin G fraction of serum.
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