[HTML][HTML] A distinct cytokine and chemokine profile at the genital mucosa is associated with HIV-1 protection among HIV-exposed seronegative commercial sex workers
J Lajoie, J Juno, A Burgener, S Rahman, K Mogk… - Mucosal …, 2012 - Elsevier
The predominance of HIV-1 sexual transmission requires a greater understanding of the
interaction between HIV-1 and the mucosal immune system. The study of HIV-1-exposed
seronegative (HESN) individuals serves as a model to identify the correlates of protection
and to aid in microbicide development. A total of 22 cytokines/chemokines were analyzed at
the systemic and mucosal compartments in 57 HESN, 51 HIV-1-negative, and 67 HIV-1-
infected commercial sex workers from Nairobi, Kenya. HESN individuals had significantly …
interaction between HIV-1 and the mucosal immune system. The study of HIV-1-exposed
seronegative (HESN) individuals serves as a model to identify the correlates of protection
and to aid in microbicide development. A total of 22 cytokines/chemokines were analyzed at
the systemic and mucosal compartments in 57 HESN, 51 HIV-1-negative, and 67 HIV-1-
infected commercial sex workers from Nairobi, Kenya. HESN individuals had significantly …