[HTML][HTML] Percentage of smudge cells on routine blood smear predicts survival in chronic lymphocytic leukemia
GS Nowakowski, JD Hoyer, TD Shanafelt… - Journal of Clinical …, 2009 - ncbi.nlm.nih.gov
GS Nowakowski, JD Hoyer, TD Shanafelt, CS Zent, TG Call, ND Bone, B LaPlant…
Journal of Clinical Oncology, 2009•ncbi.nlm.nih.govPurpose Smudge cells are ruptured chronic lymphocytic leukemia (CLL) cells appearing on
the blood smears of CLL patients. Our recent findings suggest that the number of smudge
cells may have important biologic correlations rather than being only an artifact of slide
preparation. In this study, we evaluated whether the smudge cell percentage on a blood
smear predicted survival of CLL patients.
the blood smears of CLL patients. Our recent findings suggest that the number of smudge
cells may have important biologic correlations rather than being only an artifact of slide
preparation. In this study, we evaluated whether the smudge cell percentage on a blood
smear predicted survival of CLL patients.
Abstract
Purpose
Smudge cells are ruptured chronic lymphocytic leukemia (CLL) cells appearing on the blood smears of CLL patients. Our recent findings suggest that the number of smudge cells may have important biologic correlations rather than being only an artifact of slide preparation. In this study, we evaluated whether the smudge cell percentage on a blood smear predicted survival of CLL patients.
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