The bone lining cell: a distinct phenotype?
SC Miller, WSS Jee - Calcified tissue international, 1987 - Springer
SC Miller, WSS Jee
Calcified tissue international, 1987•SpringerIt is argued that the flat cells that line nonremodeling endosteal bone surfaces are a distinct
phenotype. These cells have a distinct morphology and they most likely have important
functional roles in skeletal physiology, metabolism, and remodeling. For these reasons this
cell seems deserving of a proper name. The name bone lining cell seems to have gained
some acceptance but there will be continued confusion as long as skeletologists use this
same term to generically describe cells that line bone surfaces, regardless of their actual …
phenotype. These cells have a distinct morphology and they most likely have important
functional roles in skeletal physiology, metabolism, and remodeling. For these reasons this
cell seems deserving of a proper name. The name bone lining cell seems to have gained
some acceptance but there will be continued confusion as long as skeletologists use this
same term to generically describe cells that line bone surfaces, regardless of their actual …
Summary
It is argued that the flat cells that line nonremodeling endosteal bone surfaces are a distinct phenotype. These cells have a distinct morphology and they most likely have important functional roles in skeletal physiology, metabolism, and remodeling. For these reasons this cell seems deserving of a proper name. The namebone lining cell seems to have gained some acceptance but there will be continued confusion as long as skeletologists use this same term to generically describe cells that line bone surfaces, regardless of their actual identity.
Springer