Intrahepatic cholestasis of pregnancy: a French prospective study

Y Bacq, T Sapey, M Brechot, F Pierre, A Fignon… - Hepatology, 1997 - journals.lww.com
The aim of this prospective study was to analyze the characteristics of intrahepatic
cholestasis of pregnancy (ICP) in a French population. From 1989 to 1995 we studied 50
consecutive pregnant women with ICP (41 single, 7 twin, and 2 triplet pregnancies) referred
for hepatologic consultation. All patients suffered from pruritus and/or jaundice associated
with elevated fasting serum levels of total bile acids (mean 49 micromol/L, range 7-290). No
patients had concomitant liver disease and all recovered normal liver function after delivery …